Chondroitin Sulfate Sodium

Chondroitin sulfate sodium occurs naturally in the body and it is also derived from animal sources like bovine cartilage, shark cartilage.

Chondroitin sulfate sodium is also produced synthetically.the word chondroitin comes from Greek word Chondros which means Cartilage

Chondroitin sulfate sodium is one type of glycosaminoglycan.

Chondroitin sulfate sodium consists of linear polysaccharide chains it is composed of repeating disaccharide unit Glucuronic acid (GlcA) and N-acetyl galactosamine (GalNAc).

Chondroitin sulfate sodium is one of the building blocks of cartilage in the joints breakdown. Chondroitin sulfate sodium is a dietary supplement that helps cartilage retain water and gives elasticity

According to various positions of sulfate, there are different types of Chondroitin sulfate sodium, Chondroitin 4- sulfate, Chondroitin 6- sulfate, Chondroitin 2, 6- sulfate (chondroitin sulfate-D), Chondroitin 4, 6- sulfate (chondroitin sulfate-E)it is extracted and isolation from Squid cartilage for the first time

Chondroitin sulfate-B also known as Dermatan sulfate.

There are two main types of Chondroitin sulfate sodium, A and C, which refers in the position of their sulfate.

Sulfate A: Sulfated at position 4, also known as Chondroitin 4- sulfate.It is extracted from bovine cartilage.

Sulfate C: Sulfated at position 6, also known as Chondroitin 6- sulfate. It is extract from Shark Cartilage.

Chemical structure of chondroitin sulfate sodium chain. Chondroitin-4-sulfate: R1 = H; R2 = SO3H; R3 = H. Chondroitin-6-sulfate: R1 = SO3H; R2, R3 = H.

CAS No: 9082-07-9

• Chondroitin sulfate sodium is enzymatic ally dissolved, precipitated, crystallization, Dried and finally to get the finished product.
• It is white/ off white/pale yellow colored powder, Odourless and tasteless easily soluble in water, insoluble in ethanol acetone and other organic solvents.
• Chondroitin sulfate sodium is hygroscopic powder.

Complex properties of Chondroitin sulfate sodium:

• Chondroitin sulfate sodium is a kind of negatively charged polysaccharide, it has many free carboxyl and sulfate groups throughout its chain.
• Chondroitin sulfate sodium could interact with metal ions and some other substrates with a positive charge.

Functions of Chondroitin sulfate sodium:

• Chondroitin sulfate sodium primarily protects collagen fibers, promotes the growth of fibers in the matrix, and improves blood circulation.
• It facilitates the absorption of serums and the reduction of inflammation.
• In cartilage,chondroitin binds collagen and hold fibers in a tight strong network.
• Chondroitin sulfate sodium is a anti coagulants(blood thinner) because it is similar to Heparin. Chondroitin sulfate sodium also improved blood thinning effects.

Applications of Chondroitin sulfate sodium:

• Oral care products
• Skin care products
• Hair care products
• Sunscreen products
• Nail and lip care products

Health benefits of Chondroitin sulfate sodium

• Chondroitin sulfate sodium provides the building blocks for the body to produce new Cartilage.
• Chondroitin sulfate sodium can supplements calcium, preventing OESTOARTHRITIS and reducing back pain, shoulder painand arthritis
• Decrease Join pains and joint inflammation
• It is used in dietary supplements as an alternative medicine to treat OESTOARTHRITIS and CATARACTS.
• Activate connective tissues and cells, repairing cartilage tissue and preventing cartilage degradation.

a) Joint health treatment

• Oral supplements of Chondroitin sulfate sodium can help to manage joint discomfort, especially in the knees,hip,hand and spine.
• They also able to manage the progression of joint conditions.

b) Skin health supports

• Chondroitin sulfate sodium supplements can help to manage the chronic skin conditions.
• Chondroitin sulfate sodium fight against wrinkles and fine lines. It keeps skin hydrated and supports elasticity.

c) Maintains Healthy Eyes

• One of the benefits of chondroitin sulfate maintaining healthy eyes.
• In fact, it is often present in drops for dry eyes. The FDA has also approved it for cataract surgery as it protects eyes.
• Chondroitin sulfate also useful for preserving corneas during transport for corneal transplant surgery.

d) Lower risk of Heart attacks

• Chondroitin sulfate sodium supplements can help to prevent heart attacks.
• Chondroitin sulfate sodium has anti-thrombogenic properties that meansto prevent the formation of blood clots in the blood stream.

e) Treats Urinary Tract Infections (UTI)

• chondroitin sulfate helps reduce the number of UTIs(Urinary Tract Infections)
• When the bacteria enter through the urethra and multiply in the bladder.
• Urinary tract infections are dangerous, and if the infection spreads to the kidneys, both men and women can suffer from such infections